Center for Integrated Solutions for Infectious Diseases

From modulating immune responses and inflammation, training immunity, interacting with pathogens, creating dysbiosis, and altering metabolism and pathogen environments, the over 100 trillion microbial cells making up the individual human microbiome likely plays a critical role in infection. We are working, for example, to elucidate microbe-immune interactions and how commensal organisms can educate immunity on the skin or gut, and how their metabolites interact with host immune cells and pathogens to impact immune function and infection outcome.