Center for Integrated Solutions for Infectious Diseases

Publications

An inducible CRISPRi system for phenotypic analysis of essential genes in Pseudomonas aeruginosa

Sullivan JR., Ferrara KM., Barrick R., Romano KP., Warrier T., Hung DT.

mBio, 2026 February 11

Genomic comparison and phenotypic characterization of Pseudomonas aeruginosa isolates across environmental and diverse clinical isolation sites

Penaranda C., Brenner EP., Clatworthy AE., Cosimi LA., Ravi J., Hung DT.

mSystems, 2026 February 05

Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation

Pfeifer K., Van Cura D., Wu KJY., Balskus EP.

Nature, 2026 February 04

Bacterial immune activation via supramolecular assembly with phage triggers

Zhang T., Lyu Y., Beck CR., Iqbal N., Barbosa R., Ghanbarpour A., Laub MT.

Nature, 2026 February 04

Bronchial stenosis after lung transplant: Risk factors and clinical outcomes

Coppolino A., Maurer R., Woehl E., Connolly EM., Chamberlin E., Goldberg HJ., Jacob SS., Lee SF., Kennedy JC., Sheikh A., O’Neill AJ., Gupta S., Hernandez Acosta RA., Kovac V., Keshk M., Hackmann A., Dunning J., Sharma NS., Baden LR., Woolley AE.

JHLT Open, 2026 February 02

Quantifying the real-world impact of antibiotic use and genetic determinants of resistance on gonococcal dynamics

Helekal D., Mortimer TD., Mukherjee A., Gentile G., Le Van A., Blomqvist S., Nicholas RA., Jerse AE., Palace SG., Grad YH.

Nat Microbiol, 2026 January 30

Epstein-barr virus latent membrane protein 1 targets cIAP1, cIAP2 and TRAF2 for proteasomal degradation to activate the non-canonical NF-κB pathway

Sun Y., Li S., Mitra B., Zhong L., Zhang A., Gewurz BE.

PLoS Pathog, 2026 January 26

Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases

Jaiswal A., Kooistra T., Pokatayev V., Bastos HN., Santos RF., Sarraf TR., Segerstolpe Å., Lin C., Amir-Zilberstein L., Twardus S., Shannon K., Murphy SP., Knipe R., Ganzleben IK., Black KE., Delorey TM., Graham DB., Hung YP., Hariri LP., Deguine J., Carvalho A., Medoff BD., Xavier RJ.

Cell Genom, 2026 January 22

Vibrio cholerae serotype impacts pathogenicity

Zingl FG., Leitner DR., Fakoya B., Morano AA., Waldor MK.

Nat Commun, 2026 January 19

Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity

Rush JS, Wertheimer JD, Goldberg SD, Raymond D, Szuchnicki M, Baltus AJ, Branson J, Stratton CF, Patrick AN, Steele R, Adhikary S, Del Rosario A, Liu A, Gomersall NJ, Chung M, Ranaghan MJ, Gu X, Brandt M, Cao Z, Bebenek A, Oliver BA, Hoebe K, Szewczuk LM, Venable JD, Graham DB, Towne J, Xavier RJ.

Cell, 2026 January 17

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