Center for Integrated Solutions for Infectious Diseases

Publications

Unravelling bacterial complexity at high resolution with single-cell transcriptomics

Clatworthy AE., DiNatale VP., Burgos-Robles E., Lopes F., Smillie C., Hung DT.

Nat Microbiol, 2026 May 01

Mechanisms of inflammatory bowel diseases: Insights from human genetics and chemical biology

Graham DB., Xavier RJ.

Immunity, 2026 April 27

An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion

Steinberg R., Pust MM., Arias-Rojas A., Pishchany G., Ramsey KA., Kieninger E., Moeller A., Casaulta C., Hilty M., Latzin P., SCILD Study Group, BILD Study Group, Korten I., Xavier RJ.

Cell Host Microbe, 2026 April 20

An affinity reagent-conjugated biotin ligase for amplified cell surface labelling in vitro and in vivo

Holden B, Mutaher M, Raychowdhury R, Bakalar M, Lopez A, Schwartz MA, Olajide E, Santos M, Hacohen N.

Sci Rep, 2026 April 08

Chemiluminescent Probes Allow for the Rapid Identification of Colibactin-Producing Bacteria

Aguilar Ramos MA., Gutkin S., David M., Shabat D., Balskus EP.

JACS Au, 2026 April 06

DefensePredictor: A machine learning model to discover prokaryotic immune systems

DeWeirdt PC, Mahoney EM, Laub MT.

Science, 2026 April 02

Population and single-cell analyses reveal immune cell-specific expression profiles associated with Alzheimer’s disease risk

Lindbohm JV, Stražar M, Lee HM, Ashenberg O, Mars N, Sipilä PN, Ripatti S, Graham D, Kivimäki M, Xavier RJ.

Alzheimers Dement, 2026 March 22

Genetic background modulates zoliflodacin and gepotidacin cross-resistance and fitness in Neisseria gonorrhoeae

Mukherjee A, Blomqvist SOP, Helekal D, Das AA, Palace SG, Grad YH.

J Infect Dis, 2026 March 20

Perspectives on the 2026 ISHLT Consensus Statement on Clinical Cardiac Xenotransplantation

Mehra MR, Mohiuddin MM, Reichart B, Abicht JM, Boulet J, Cooper DKC, Cowan PJ, Crespo-Leiro MG, Denner J, Fishman JA, Griffith BP, Hawthorne WJ, Joyce E, Konstantinov IE, Lala A, Langin M, Padera RF Jr, Pierson RN 3rd, Schnieke A, Scobie L, Uber PA, Wolf E, Woolley AE.

J Heart Lung Transplant, 2026 March 19

Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy

He C., Amodio M., Ashenberg O., Wucherpfennig KW., Xavier RJ., Uhler C.

Nat Commun, 2026 March 12

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