Publications
Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity
Rush JS, Wertheimer JD, Goldberg SD, Raymond D, Szuchnicki M, Baltus AJ, Branson J, Stratton CF, Patrick AN, Steele R, Adhikary S, Del Rosario A, Liu A, Gomersall NJ, Chung M, Ranaghan MJ, Gu X, Brandt M, Cao Z, Bebenek A, Oliver BA, Hoebe K, Szewczuk LM, Venable JD, Graham DB, Towne J, Xavier RJ.
Cell, 2026 January 17
Flavoaffinins, Elusive Cellulose-Binding Natural Products from an Anaerobic Bacterium
Kountz DJ, Yu R, Lee JH, Maloney KN, Balskus EP.
J Am Chem Soc, 2026 January 15
Intelectin-2 is a broad-spectrum antimicrobial lectin
Dugan AE, Syangtan D, Nonnecke EB, Chorghade RS, Peiffer AL, Yao JJ, Ille-Bunn J, Sergio D, Pishchany G, Dhennezel C, Vlamakis H, Bae S, Johnson S, Ellis C, Ghosh S, Alty JW, Barnes CE, Krupkin M, Cárcamo-Oyarce G, Ribbeck K, Xavier RJ, Bevins CL, Kiessling LL.
Nat Commun, 2026 January 13
Training Tomorrow’s Leaders in Cancer Immunology
Tan Y, Kim BJ, Mujal AM, Chen ACY, Weis AM, Bergaggio E, Micevic G, Xie H, Park JS, Hor JL, Papanicolaou M, Shobaki N, Domizi P, Delconte RB, Vendramin R, Hegde S, Han S, Su Y, Hacohen N.
Cancer Immunol Res, 2026 January 12
Bridging AI and biology: Foundation models meet human physiology and disease
Ashenberg O, Xavier RJ.
Med, 2026 January 10
Safety and immunogenicity of PanChol, a single-dose live-attenuated oral cholera vaccine: results from a phase 1a, double-blind, randomised, placebo-controlled trial
Leitner DR, Walsh SR, Suzuki M, Desjardins M, Hannaford A, Sherman AC, Levine H, Carr L, Hammerness E, Osaki A, Sullivan E, Wang B, Balazs GI, Park Chang JB, Slater DM, Puri N, Kuehl CJ, Chen WH, Harris JB, Piantadosi S, Baden LR, Waldor MK; PanChol study group.
Lancet Infect Dis, 2026 January 10
Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study
Kline MC, Oliveira Roster K, Helekal D, Rumpler E, Grad YH.
Clin Infect Dis, 2026 January 08
Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit
Pokatayev V, Jaiswal A, Shih AR, Segerstolpe Å, Li B, Creasey EA, Zhao Y, Lin C, Murphy S, Chou CH, Graham DB, Xavier RJ.
Nature, 2026 January 07
Quantifying host-microbe interactions with bacterial lineage tracing
Campbell IW, Hullahalli K, Waldor MK.
Science, 2026 January 01
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly
Yu Z, Sathyanarayana P, Liu C, Tan JMJ, Yang P, Das B, Hu S, Fan X, Ji C, Weller SK, Shekhar M, Coen DM, Kranzusch PJ, Loparo JJ, Abraham J.
Cell, 2025 December 30
