Center for Integrated Solutions for Infectious Diseases

Publications

Lysine-specific histone demethylase complex restricts Epstein-Barr virus lytic reactivation

Liao Y, Yan J, Kong IY, Li Z, Ding W, Clark S, Maestri D, Yoshida T, Giulino-Roth L, Gewurz BE.

Nat Microbiol, 2025 November 01

Human immunodeficiency virus and antiretroviral therapies exert distinct influences across diverse gut microbiomes

Jabbar KS, Priya S, Xu J, Das Adhikari U, Pishchany G, Mohamed ATM, Johansen J, Thurimella K, McCabe C, Vlamakis H, Okello S, Delorey TM, Lankowski A, Mosepele M, Siedner MJ, Plichta DR, Kwon DS, Xavier RJ.

Nat Microbiol, 2025 October 31

Anoxia activates CRISPR-Cas immunity in the mouse intestine

Campbell IW, Basta DW, Zingl FG, Sullivan EJ, Doranga S, Waldor MK.

Nat Microbiol, 2025 October 30

Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation

Tan P, Jaiswal A, Murphy SP, Brown EM, Wheeler H, Su CW, Finan EP, Jasso GJ, Shi HN, Graham DB, Delorey TM, Deguine J, Xavier RJ.

Science, 2025 October 30

A Multiplexed, Target-Based Phenotypic Screening Platform Using CRISPR Interference in Mycobacterium abscessus

Neo DM, Ben-Zion I, Bagnall J, Solomon MY, Bond AN, Gath E, Zhang S, Shoresh N, Gomez J, Hung DT.

ACS Infect Dis, 2025 October 27

Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism

Goering ER, Clatworthy AE, Parada-Kusz M, Bagnall J, Hung DT.

PLoS Pathog, 2025 October 23

Multi-environment deep mutational scanning reveals the distribution of temperature-sensitive variants in a bacterial kinase

Ghose DA, Soderstrom CBW, Mahoney EM, Laub MT.

Cell Rep, 2025 October 17

Emergence of antiphage functions from random sequence libraries reveals mechanisms of gene birth

Frumkin I, Vassallo CN, Chen YH, Laub MT.

Proc Natl Acad Sci U S A, 2025 October 15

The carbapenem inoculum effect provides insights into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales

Jaramillo Cartagena A, Taylor KL, Lopez LC, Su J, Smith JT, Manson AL, Chen JD, Pierce VM, Earl AM, Bhattacharyya RP.

mBio, 2025 October 02

Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation

Chen X, Hwang HS, Li B, Zhao Y, Ghosh K, Deng L, Creasey EA, Ashenberg O, Graham DB, Xavier RJ.

Proc Natl Acad Sci U S A, 2025 September 18

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